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Phosphorylation by Dyrk1A of Clathrin Coated Vesicle-Associated Proteins: Identification of the Substrate Proteins and the Effects of Phosphorylation

Dyrk1A phosphorylated multiple proteins in the clathrin-coated vesicle (CCV) preparations obtained from rat brains. Mass spectrometric analysis identified MAP1A, MAP2, AP180, and α- and β-adaptins as the phosphorylated proteins in the CCVs. Each protein was subsequently confirmed by [(32)P]-labeling...

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Detalles Bibliográficos
Autores principales: Murakami, Noriko, Bolton, David C., Kida, Elizabeth, Xie, Wen, Hwang, Yu-Wen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3325943/
https://www.ncbi.nlm.nih.gov/pubmed/22514676
http://dx.doi.org/10.1371/journal.pone.0034845