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Gremlin-1 Induces BMP-Independent Tumor Cell Proliferation, Migration, and Invasion
Gremlin-1, a bone morphogenetic protein (BMP) antagonist, is overexpressed in various cancerous tissues but its role in carcinogenesis has not been established. Here, we report that gremlin-1 binds various cancer cell lines and this interaction is inhibited by our newly developed gremlin-1 antibody,...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2012
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3325980/ https://www.ncbi.nlm.nih.gov/pubmed/22514712 http://dx.doi.org/10.1371/journal.pone.0035100 |