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Zebrafish Agr2 Is Required for Terminal Differentiation of Intestinal Goblet Cells

BACKGROUND: Mammalian Anterior Gradient 2 (AGR2) is a protein disulfide isomerase that is required for the production of intestinal mucus and Paneth and goblet cell homeostasis. However, whether increased endoplasmic reticulum (ER) stress occurs in Agr2(−/−) mice remains a controversial issue. METHO...

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Detalles Bibliográficos
Autores principales: Chen, Yi-Chung, Lu, Yu-Fen, Li, I-Chen, Hwang, Sheng-Ping L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3326001/
https://www.ncbi.nlm.nih.gov/pubmed/22514630
http://dx.doi.org/10.1371/journal.pone.0034408