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The Notch Ligand Delta-Like 4 Regulates Multiple Stages of Early Hemato-Vascular Development

BACKGROUND: In mouse embryos, homozygous or heterozygous deletions of the gene encoding the Notch ligand Dll4 result in early embryonic death due to major defects in endothelial remodeling in the yolk sac and embryo. Considering the close developmental relationship between endothelial and hematopoie...

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Detalles Bibliográficos
Autores principales:	Laranjeiro, Ricardo, Alcobia, Isabel, Neves, Hélia, Gomes, Andreia C., Saavedra, Pedro, Carvalho, Catarina C., Duarte, António, Cidadão, António, Parreira, Leonor
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3326024/ https://www.ncbi.nlm.nih.gov/pubmed/22514637 http://dx.doi.org/10.1371/journal.pone.0034553

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