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DotU and VgrG, Core Components of Type VI Secretion Systems, Are Essential for Francisella LVS Pathogenicity

The Gram-negative bacterium Francisella tularensis causes tularemia, a disease which requires bacterial escape from phagosomes of infected macrophages. Once in the cytosol, the bacterium rapidly multiplies, inhibits activation of the inflammasome and ultimately causes death of the host cell. Of impo...

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Detalles Bibliográficos
Autores principales:	Bröms, Jeanette E., Meyer, Lena, Lavander, Moa, Larsson, Pär, Sjöstedt, Anders
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3326028/ https://www.ncbi.nlm.nih.gov/pubmed/22514651 http://dx.doi.org/10.1371/journal.pone.0034639

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