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Molecular Mechanism Underlying Persistent Induction of LCN2 by Lipopolysaccharide in Kidney Fibroblasts

The neutrophil gelatinase-associated lipocalin 2 (LCN2) is a critical inflammatory mediator persistently induced during endotoxemia, contributing to tubular damage and kidney failure. The intracellular process responsible for persistent induction of LCN2 by bacterial endotoxin Lipopolysaccharide (LP...

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Detalles Bibliográficos
Autores principales: Glaros, Trevor, Fu, Yan, Xing, Jianhua, Li, Liwu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3326042/
https://www.ncbi.nlm.nih.gov/pubmed/22514649
http://dx.doi.org/10.1371/journal.pone.0034633