Visualising molecular juggling within a B(12)-dependent methyltransferase complex

Derivatives of vitamin B(12) are used in methyl group transfer in biological processes as diverse as methionine synthesis in humans and CO(2) fixation in acetogenic bacteria(1–3). This seemingly straightforward reaction requires large, multimodular enzyme complexes that adopt multiple conformations...

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Detalles Bibliográficos
Autores principales: Kung, Yan, Ando, Nozomi, Doukov, Tzanko I., Blasiak, Leah C., Bender, Güneş, Seravalli, Javier, Ragsdale, Stephen W., Drennan, Catherine L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3326194/
https://www.ncbi.nlm.nih.gov/pubmed/22419154
http://dx.doi.org/10.1038/nature10916

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3326194/
https://www.ncbi.nlm.nih.gov/pubmed/22419154
http://dx.doi.org/10.1038/nature10916

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