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Visualising molecular juggling within a B(12)-dependent methyltransferase complex
Derivatives of vitamin B(12) are used in methyl group transfer in biological processes as diverse as methionine synthesis in humans and CO(2) fixation in acetogenic bacteria(1–3). This seemingly straightforward reaction requires large, multimodular enzyme complexes that adopt multiple conformations...
Autores principales: | Kung, Yan, Ando, Nozomi, Doukov, Tzanko I., Blasiak, Leah C., Bender, Güneş, Seravalli, Javier, Ragsdale, Stephen W., Drennan, Catherine L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3326194/ https://www.ncbi.nlm.nih.gov/pubmed/22419154 http://dx.doi.org/10.1038/nature10916 |
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