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Opposing roles of CXCR4 and CXCR7 in breast cancer metastasis

INTRODUCTION: CXCL12-CXCR4 signaling has been shown to play a role in breast cancer progression by enhancing tumor growth, angiogenesis, triggering cancer cell invasion in vitro, and guiding cancer cells to their sites of metastasis. However, CXCR7 also binds to CXCL12 and has been recently found to...

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Detalles Bibliográficos
Autores principales:	Hernandez, Lorena, Magalhaes, Marco AO, Coniglio, Salvatore J, Condeelis, John S, Segall, Jeffrey E
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2011
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3326570/ https://www.ncbi.nlm.nih.gov/pubmed/22152016 http://dx.doi.org/10.1186/bcr3074

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