Cargando…
The microRNA miR-34 modulates aging and neurodegeneration in Drosophila
Human neurodegenerative diseases possess the temporal hallmark of afflicting the elderly population. Hence, aging is among the most significant factors to impinge on disease onset and progression(1), yet little is known of molecular pathways that connect these processes. Central to understanding thi...
Autores principales: | Liu, Nan, Landreh, Michael, Cao, Kajia, Abe, Masashi, Hendriks, Gert-Jan, Kennerdell, Jason, Zhu, Yongqing, Wang, Li-San, Bonini, Nancy M |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2012
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3326599/ https://www.ncbi.nlm.nih.gov/pubmed/22343898 http://dx.doi.org/10.1038/nature10810 |
Ejemplares similares
-
Impact of age-associated increase in 2′-O-methylation of miRNAs on aging and neurodegeneration in Drosophila
por: Abe, Masashi, et al.
Publicado: (2014) -
MiR-34 inhibits polycomb repressive complex 2 to modulate chaperone expression and promote healthy brain aging
por: Kennerdell, Jason R., et al.
Publicado: (2018) -
Modulation of the Aging Drosophila Brain and Susceptibility to Neurodegeneration
por: Bonini, Nancy
Publicado: (2020) -
The exonuclease Nibbler regulates age-associated traits and modulates piRNA length in Drosophila
por: Feltzin, Virzhiniya L, et al.
Publicado: (2015) -
Loss of miR‐34 in Drosophila dysregulates protein translation and protein turnover in the aging brain
por: Srinivasan, Ananth R., et al.
Publicado: (2022)