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Facile synthesis of nitrophenyl 2-acetamido-2-deoxy-α-D-mannopyranosides from ManNAc-oxazoline

The synthetic procedures for a large-scale preparation of o- and p-nitrophenyl 2-acetamido-2-deoxy-α-D-mannopyranoside are described. The synthetic pathway employs the glycosylation of phenol with ManNAc oxazoline, followed by nitration of the aromatic moiety yielding a separable mixture of the o- a...

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Detalles Bibliográficos
Autores principales: Křenek, Karel, Šimon, Petr, Weignerová, Lenka, Fliedrová, Barbora, Kuzma, Marek, Křen, Vladimír
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Beilstein-Institut 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3326621/
https://www.ncbi.nlm.nih.gov/pubmed/22509213
http://dx.doi.org/10.3762/bjoc.8.48