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Targeting Mnks for Cancer Therapy

Deregulation of protein synthesis is a common event in human cancer and a key player in translational control is eIF4E. Elevated expression levels of eIF4E promote cancer development and progression. Recent findings suggest that eIF4E activity is a key determinant of the PI3K/Akt/mTOR and Ras/Raf/ME...

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Detalles Bibliográficos
Autores principales:	Hou, Jinqiang, Lam, Frankie, Proud, Christopher, Wang, Shudong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2012
Materias:	Reviews
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3326643/ https://www.ncbi.nlm.nih.gov/pubmed/22392765

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