NT5E (CD73) is epigenetically regulated in malignant melanoma and associated with metastatic site specificity

BACKGROUND: Novel prognostic biomarkers and therapeutic strategies are urgently required for malignant melanoma. Ecto-5-prime-nucleotidase (NT5E; CD73) overexpression has been reported in several human cancers. The mechanism(s) underlying deregulated expression and the clinical consequences of chang...

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Detalles Bibliográficos
Autores principales: Wang, H, Lee, S, Nigro, C Lo, Lattanzio, L, Merlano, M, Monteverde, M, Matin, R, Purdie, K, Mladkova, N, Bergamaschi, D, Harwood, C, Syed, N, Szlosarek, P, Briasoulis, E, McHugh, A, Thompson, A, Evans, A, Leigh, I, Fleming, C, Inman, G J, Hatzimichael, E, Proby, C, Crook, T
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2012
Materias:
Molecular Diagnostics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3326678/
https://www.ncbi.nlm.nih.gov/pubmed/22454080
http://dx.doi.org/10.1038/bjc.2012.95

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3326678/
https://www.ncbi.nlm.nih.gov/pubmed/22454080
http://dx.doi.org/10.1038/bjc.2012.95

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