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Zimelidine attenuates the development of tolerance to morphine-induced antinociception
OBJECTIVES: The aim of this study was to investigate effect of zimelidine (a serotonin reuptake inhibitor) on morphine-induced tolerance in rats. MATERIALS AND METHODS: Male Wistar albino rats weighing 160–180 g were used in these experiments (n=72). A 3-day cumulative dosing regimen was used for th...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Medknow Publications & Media Pvt Ltd
2012
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3326915/ https://www.ncbi.nlm.nih.gov/pubmed/22529478 http://dx.doi.org/10.4103/0253-7613.93851 |