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The Contegra conduit: Late outcomes in right ventricular outflow tract reconstruction
OBJECTIVES: To report the clinical outcomes (early death, late death, and rate of reintervention) and performance of the Contegra conduit as a right ventricle outflow tract implant and to determine the risk factors for early reintervention. METHODS: Forty-nine Contegra conduits were implanted betwee...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Medknow Publications & Media Pvt Ltd
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3327010/ https://www.ncbi.nlm.nih.gov/pubmed/22529597 http://dx.doi.org/10.4103/0974-2069.93706 |
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author | Holmes, Anthony A Co, Steve Human, Derek G LeBlanc, Jacques G Campbell, Andrew IM |
author_facet | Holmes, Anthony A Co, Steve Human, Derek G LeBlanc, Jacques G Campbell, Andrew IM |
author_sort | Holmes, Anthony A |
collection | PubMed |
description | OBJECTIVES: To report the clinical outcomes (early death, late death, and rate of reintervention) and performance of the Contegra conduit as a right ventricle outflow tract implant and to determine the risk factors for early reintervention. METHODS: Forty-nine Contegra conduits were implanted between January 2002 and June 2009. Data collection was retrospective. The mean age and follow-up duration of Contegra recipients was 3.5 ± 4.6 years and 4.2 ± 2.0 years, respectively. RESULTS: There were three deaths (two early, one late), giving a survival rate of 93.9%. The rate of conduit-related reintervention was 19.6% and was most often due to distal conduit stenosis. Age at implantation of <3 months, receipt of a conduit of 12–16 mm diameter, and a diagnosis of truncus arteriosus were each significant contributors to the rate of reintervention. CONCLUSION: The Contegra is a cost-effective and readily available solution. However, there is a limited range of larger calibers, which means that the homograft conduit (>22 mm) remains the first choice of implant in older children. The rates of reintervention are significantly higher with a diagnosis of truncus arteriosus, age at implantation of <3 months, and implantation of conduits sized 12–16 mm. |
format | Online Article Text |
id | pubmed-3327010 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2012 |
publisher | Medknow Publications & Media Pvt Ltd |
record_format | MEDLINE/PubMed |
spelling | pubmed-33270102012-04-23 The Contegra conduit: Late outcomes in right ventricular outflow tract reconstruction Holmes, Anthony A Co, Steve Human, Derek G LeBlanc, Jacques G Campbell, Andrew IM Ann Pediatr Cardiol Original Article OBJECTIVES: To report the clinical outcomes (early death, late death, and rate of reintervention) and performance of the Contegra conduit as a right ventricle outflow tract implant and to determine the risk factors for early reintervention. METHODS: Forty-nine Contegra conduits were implanted between January 2002 and June 2009. Data collection was retrospective. The mean age and follow-up duration of Contegra recipients was 3.5 ± 4.6 years and 4.2 ± 2.0 years, respectively. RESULTS: There were three deaths (two early, one late), giving a survival rate of 93.9%. The rate of conduit-related reintervention was 19.6% and was most often due to distal conduit stenosis. Age at implantation of <3 months, receipt of a conduit of 12–16 mm diameter, and a diagnosis of truncus arteriosus were each significant contributors to the rate of reintervention. CONCLUSION: The Contegra is a cost-effective and readily available solution. However, there is a limited range of larger calibers, which means that the homograft conduit (>22 mm) remains the first choice of implant in older children. The rates of reintervention are significantly higher with a diagnosis of truncus arteriosus, age at implantation of <3 months, and implantation of conduits sized 12–16 mm. Medknow Publications & Media Pvt Ltd 2012 /pmc/articles/PMC3327010/ /pubmed/22529597 http://dx.doi.org/10.4103/0974-2069.93706 Text en Copyright: © Annals of Pediatric Cardiology http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Original Article Holmes, Anthony A Co, Steve Human, Derek G LeBlanc, Jacques G Campbell, Andrew IM The Contegra conduit: Late outcomes in right ventricular outflow tract reconstruction |
title | The Contegra conduit: Late outcomes in right ventricular outflow tract reconstruction |
title_full | The Contegra conduit: Late outcomes in right ventricular outflow tract reconstruction |
title_fullStr | The Contegra conduit: Late outcomes in right ventricular outflow tract reconstruction |
title_full_unstemmed | The Contegra conduit: Late outcomes in right ventricular outflow tract reconstruction |
title_short | The Contegra conduit: Late outcomes in right ventricular outflow tract reconstruction |
title_sort | contegra conduit: late outcomes in right ventricular outflow tract reconstruction |
topic | Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3327010/ https://www.ncbi.nlm.nih.gov/pubmed/22529597 http://dx.doi.org/10.4103/0974-2069.93706 |
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