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The Contegra conduit: Late outcomes in right ventricular outflow tract reconstruction

OBJECTIVES: To report the clinical outcomes (early death, late death, and rate of reintervention) and performance of the Contegra conduit as a right ventricle outflow tract implant and to determine the risk factors for early reintervention. METHODS: Forty-nine Contegra conduits were implanted betwee...

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Autores principales: Holmes, Anthony A, Co, Steve, Human, Derek G, LeBlanc, Jacques G, Campbell, Andrew IM
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3327010/
https://www.ncbi.nlm.nih.gov/pubmed/22529597
http://dx.doi.org/10.4103/0974-2069.93706
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author Holmes, Anthony A
Co, Steve
Human, Derek G
LeBlanc, Jacques G
Campbell, Andrew IM
author_facet Holmes, Anthony A
Co, Steve
Human, Derek G
LeBlanc, Jacques G
Campbell, Andrew IM
author_sort Holmes, Anthony A
collection PubMed
description OBJECTIVES: To report the clinical outcomes (early death, late death, and rate of reintervention) and performance of the Contegra conduit as a right ventricle outflow tract implant and to determine the risk factors for early reintervention. METHODS: Forty-nine Contegra conduits were implanted between January 2002 and June 2009. Data collection was retrospective. The mean age and follow-up duration of Contegra recipients was 3.5 ± 4.6 years and 4.2 ± 2.0 years, respectively. RESULTS: There were three deaths (two early, one late), giving a survival rate of 93.9%. The rate of conduit-related reintervention was 19.6% and was most often due to distal conduit stenosis. Age at implantation of <3 months, receipt of a conduit of 12–16 mm diameter, and a diagnosis of truncus arteriosus were each significant contributors to the rate of reintervention. CONCLUSION: The Contegra is a cost-effective and readily available solution. However, there is a limited range of larger calibers, which means that the homograft conduit (>22 mm) remains the first choice of implant in older children. The rates of reintervention are significantly higher with a diagnosis of truncus arteriosus, age at implantation of <3 months, and implantation of conduits sized 12–16 mm.
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spelling pubmed-33270102012-04-23 The Contegra conduit: Late outcomes in right ventricular outflow tract reconstruction Holmes, Anthony A Co, Steve Human, Derek G LeBlanc, Jacques G Campbell, Andrew IM Ann Pediatr Cardiol Original Article OBJECTIVES: To report the clinical outcomes (early death, late death, and rate of reintervention) and performance of the Contegra conduit as a right ventricle outflow tract implant and to determine the risk factors for early reintervention. METHODS: Forty-nine Contegra conduits were implanted between January 2002 and June 2009. Data collection was retrospective. The mean age and follow-up duration of Contegra recipients was 3.5 ± 4.6 years and 4.2 ± 2.0 years, respectively. RESULTS: There were three deaths (two early, one late), giving a survival rate of 93.9%. The rate of conduit-related reintervention was 19.6% and was most often due to distal conduit stenosis. Age at implantation of <3 months, receipt of a conduit of 12–16 mm diameter, and a diagnosis of truncus arteriosus were each significant contributors to the rate of reintervention. CONCLUSION: The Contegra is a cost-effective and readily available solution. However, there is a limited range of larger calibers, which means that the homograft conduit (>22 mm) remains the first choice of implant in older children. The rates of reintervention are significantly higher with a diagnosis of truncus arteriosus, age at implantation of <3 months, and implantation of conduits sized 12–16 mm. Medknow Publications & Media Pvt Ltd 2012 /pmc/articles/PMC3327010/ /pubmed/22529597 http://dx.doi.org/10.4103/0974-2069.93706 Text en Copyright: © Annals of Pediatric Cardiology http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Article
Holmes, Anthony A
Co, Steve
Human, Derek G
LeBlanc, Jacques G
Campbell, Andrew IM
The Contegra conduit: Late outcomes in right ventricular outflow tract reconstruction
title The Contegra conduit: Late outcomes in right ventricular outflow tract reconstruction
title_full The Contegra conduit: Late outcomes in right ventricular outflow tract reconstruction
title_fullStr The Contegra conduit: Late outcomes in right ventricular outflow tract reconstruction
title_full_unstemmed The Contegra conduit: Late outcomes in right ventricular outflow tract reconstruction
title_short The Contegra conduit: Late outcomes in right ventricular outflow tract reconstruction
title_sort contegra conduit: late outcomes in right ventricular outflow tract reconstruction
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3327010/
https://www.ncbi.nlm.nih.gov/pubmed/22529597
http://dx.doi.org/10.4103/0974-2069.93706
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