Seizures after intravenous tramadol given as premedication

A 35-year-old, 50-kg female with a history of epilepsy was scheduled for elective breast surgery (fibroadenoma) under general anaesthesia. She was given glycopyrrolate 0.2 mg, ondansetron 4 mg and tramadol 100 mg i.v. as premedication. Within 5 min, she had an acute episode of generalised tonic–clon...

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Autores principales: Raiger, Lalit Kumar, Naithani, Udita, Bhatia, Sonali, Chauhan, Sandeep Singh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2012
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3327072/
https://www.ncbi.nlm.nih.gov/pubmed/22529421
http://dx.doi.org/10.4103/0019-5049.93345
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author Raiger, Lalit Kumar
Naithani, Udita
Bhatia, Sonali
Chauhan, Sandeep Singh
author_facet Raiger, Lalit Kumar
Naithani, Udita
Bhatia, Sonali
Chauhan, Sandeep Singh
author_sort Raiger, Lalit Kumar
collection PubMed
description A 35-year-old, 50-kg female with a history of epilepsy was scheduled for elective breast surgery (fibroadenoma) under general anaesthesia. She was given glycopyrrolate 0.2 mg, ondansetron 4 mg and tramadol 100 mg i.v. as premedication. Within 5 min, she had an acute episode of generalised tonic–clonic seizure that was successfully treated with 75 mg thiopentone i.v. and after 30 min, she was given general anaesthesia with endotracheal intubation. Surgery, intra-operative period, extubation and post-operative period were uneventful. We conclude that tramadol may provoke seizures in patients with epilepsy even within the recommended dose range.
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spelling pubmed-33270722012-04-23 Seizures after intravenous tramadol given as premedication Raiger, Lalit Kumar Naithani, Udita Bhatia, Sonali Chauhan, Sandeep Singh Indian J Anaesth Case Report A 35-year-old, 50-kg female with a history of epilepsy was scheduled for elective breast surgery (fibroadenoma) under general anaesthesia. She was given glycopyrrolate 0.2 mg, ondansetron 4 mg and tramadol 100 mg i.v. as premedication. Within 5 min, she had an acute episode of generalised tonic–clonic seizure that was successfully treated with 75 mg thiopentone i.v. and after 30 min, she was given general anaesthesia with endotracheal intubation. Surgery, intra-operative period, extubation and post-operative period were uneventful. We conclude that tramadol may provoke seizures in patients with epilepsy even within the recommended dose range. Medknow Publications & Media Pvt Ltd 2012 /pmc/articles/PMC3327072/ /pubmed/22529421 http://dx.doi.org/10.4103/0019-5049.93345 Text en Copyright: © Indian Journal of Anaesthesia http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Raiger, Lalit Kumar
Naithani, Udita
Bhatia, Sonali
Chauhan, Sandeep Singh
Seizures after intravenous tramadol given as premedication
title Seizures after intravenous tramadol given as premedication
title_full Seizures after intravenous tramadol given as premedication
title_fullStr Seizures after intravenous tramadol given as premedication
title_full_unstemmed Seizures after intravenous tramadol given as premedication
title_short Seizures after intravenous tramadol given as premedication
title_sort seizures after intravenous tramadol given as premedication
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3327072/
https://www.ncbi.nlm.nih.gov/pubmed/22529421
http://dx.doi.org/10.4103/0019-5049.93345
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AT bhatiasonali seizuresafterintravenoustramadolgivenaspremedication
AT chauhansandeepsingh seizuresafterintravenoustramadolgivenaspremedication

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