Genetic association study of NF-κB genes in UK Caucasian adult and juvenile onset idiopathic inflammatory myopathy

Objective. Treatment-resistant muscle wasting is an increasingly recognized problem in idiopathic inflammatory myopathy (IIM). TNF-α is thought to induce muscle catabolism via activation of nuclear factor-kappa B (NF-κB). Several genes share homology with the NF-κB family of proteins. This study inv...

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Detalles Bibliográficos
Autores principales: Chinoy, Hector, Li, Charles K.-C., Platt, Hazel, Fertig, Noreen, Varsani, Hemlata, Gunawardena, Harsha, Betteridge, Zoe, Oddis, Chester V., McHugh, Neil J., Wedderburn, Lucy R., Ollier, William E. R., Cooper, Robert G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2012
Materias:
Basic Science
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3327167/
https://www.ncbi.nlm.nih.gov/pubmed/22210660
http://dx.doi.org/10.1093/rheumatology/ker379

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