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The endosomal adaptor protein APPL1 impairs the turnover of leading edge adhesions to regulate cell migration
Cell migration is a complex process that requires the integration of signaling events that occur in distinct locations within the cell. Adaptor proteins, which can localize to different subcellular compartments, where they bring together key signaling proteins, are emerging as attractive candidates...
Autores principales: | Broussard, Joshua A., Lin, Wan-hsin, Majumdar, Devi, Anderson, Bridget, Eason, Brady, Brown, Claire M., Webb, Donna J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The American Society for Cell Biology
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3327316/ https://www.ncbi.nlm.nih.gov/pubmed/22379109 http://dx.doi.org/10.1091/mbc.E11-02-0124 |
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