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Molecular basis for phosphospecific recognition of histone H3 tails by Survivin paralogues at inner centromeres
Survivin, a subunit of the chromosome passenger complex (CPC), binds the N-terminal tail of histone H3, which is phosphorylated on T3 by Haspin kinase, and localizes the complex to the inner centromeres. We used x-ray crystallography to determine the residues of Survivin that are important in bindin...
Autores principales: | Niedzialkowska, Ewa, Wang, Fangwei, Porebski, Przemyslaw J., Minor, Wladek, Higgins, Jonathan M. G., Stukenberg, P. Todd |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The American Society for Cell Biology
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3327328/ https://www.ncbi.nlm.nih.gov/pubmed/22357620 http://dx.doi.org/10.1091/mbc.E11-11-0904 |
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