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An inactivating caspase 11 passenger mutation originating from the 129 murine strain in mice targeted for c-IAP1

A recent study revealed that ES (embryonic stem) cell lines derived from the 129 murine strain carry an inactivating mutation within the caspase 11 gene (Casp4) locus [Kayagaki, Warming, Lamkanfi, Vande Walle, Louie, Dong, Newton, Qu, Liu, Heldens, Zhang, Lee, Roose-Girma and Dixit (2011) Nature 479...

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Detalles Bibliográficos
Autores principales:	Kenneth, Niall S., Younger, J. Michael, Hughes, Elizabeth D., Marcotte, Danielle, Barker, Philip A., Saunders, Thomas L., Duckett, Colin S.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Portland Press Ltd. 2012
Materias:	Accelerated Publication
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3327503/ https://www.ncbi.nlm.nih.gov/pubmed/22332634 http://dx.doi.org/10.1042/BJ20120249

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