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Dynamics of Hepatitis B Virus Quasispecies in Association with Nucleos(t)ide Analogue Treatment Determined by Ultra-Deep Sequencing
BACKGROUND AND AIMS: Although the advent of ultra-deep sequencing technology allows for the analysis of heretofore-undetectable minor viral mutants, a limited amount of information is currently available regarding the clinical implications of hepatitis B virus (HBV) genomic heterogeneity. METHODS: T...
Autores principales: | Nishijima, Norihiro, Marusawa, Hiroyuki, Ueda, Yoshihide, Takahashi, Ken, Nasu, Akihiro, Osaki, Yukio, Kou, Tadayuki, Yazumi, Shujiro, Fujiwara, Takeshi, Tsuchiya, Soken, Shimizu, Kazuharu, Uemoto, Shinji, Chiba, Tsutomu |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3327662/ https://www.ncbi.nlm.nih.gov/pubmed/22523569 http://dx.doi.org/10.1371/journal.pone.0035052 |
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