Cargando…
Genetic Screening of New Genes Responsible for Cellular Adaptation to Hypoxia Using a Genome-Wide shRNA Library
Oxygen is a vital requirement for multi-cellular organisms to generate energy and cells have developed multiple compensatory mechanisms to adapt to stressful hypoxic conditions. Such adaptive mechanisms are intricately interconnected with other signaling pathways that regulate cellular functions suc...
Autores principales: | Yoshino, Seiko, Hara, Toshiro, Weng, Jane S., Takahashi, Yuka, Seiki, Motoharu, Sakamoto, Takeharu |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3327663/ https://www.ncbi.nlm.nih.gov/pubmed/22523603 http://dx.doi.org/10.1371/journal.pone.0035590 |
Ejemplares similares
-
NECAB3 Promotes Activation of Hypoxia-inducible factor-1 during Normoxia and Enhances Tumourigenicity of Cancer Cells
por: Nakaoka, Hiroki J., et al.
Publicado: (2016) -
The ERK signaling target RNF126 regulates anoikis resistance in cancer cells by changing the mitochondrial metabolic flux
por: Yoshino, Seiko, et al.
Publicado: (2016) -
shRNA target prediction informed by comprehensive enquiry (SPICE): a supporting system for high-throughput screening of shRNA library
por: Kamatuka, Kenta, et al.
Publicado: (2016) -
PCR-based generation of shRNA libraries from cDNAs
por: Du, Cheng, et al.
Publicado: (2006) -
Rapid Creation and Quantitative Monitoring of High Coverage shRNA Libraries
por: Bassik, Michael C., et al.
Publicado: (2009)