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No Evidence for Immune Priming in Ants Exposed to a Fungal Pathogen
There is accumulating evidence that invertebrates can acquire long-term protection against pathogens through immune priming. However, the range of pathogens eliciting immune priming and the specificity of the response remain unclear. Here, we tested if the exposure to a natural fungal pathogen elici...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3327680/ https://www.ncbi.nlm.nih.gov/pubmed/22523588 http://dx.doi.org/10.1371/journal.pone.0035372 |
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author | Reber, Anabelle Chapuisat, Michel |
author_facet | Reber, Anabelle Chapuisat, Michel |
author_sort | Reber, Anabelle |
collection | PubMed |
description | There is accumulating evidence that invertebrates can acquire long-term protection against pathogens through immune priming. However, the range of pathogens eliciting immune priming and the specificity of the response remain unclear. Here, we tested if the exposure to a natural fungal pathogen elicited immune priming in ants. We found no evidence for immune priming in Formica selysi workers exposed to Beauveria bassiana. The initial exposure of ants to the fungus did not alter their resistance in a subsequent challenge with the same fungus. There was no sign of priming when using homologous and heterologous combinations of fungal strains for exposure and subsequent challenges at two time intervals. Hence, within the range of conditions tested, the immune response of this social insect to the fungal pathogen appears to lack memory and strain-specificity. These results show that immune priming is not ubiquitous across pathogens, hosts and conditions, possibly because of immune evasion by the pathogen or efficient social defences by the host. |
format | Online Article Text |
id | pubmed-3327680 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2012 |
publisher | Public Library of Science |
record_format | MEDLINE/PubMed |
spelling | pubmed-33276802012-04-20 No Evidence for Immune Priming in Ants Exposed to a Fungal Pathogen Reber, Anabelle Chapuisat, Michel PLoS One Research Article There is accumulating evidence that invertebrates can acquire long-term protection against pathogens through immune priming. However, the range of pathogens eliciting immune priming and the specificity of the response remain unclear. Here, we tested if the exposure to a natural fungal pathogen elicited immune priming in ants. We found no evidence for immune priming in Formica selysi workers exposed to Beauveria bassiana. The initial exposure of ants to the fungus did not alter their resistance in a subsequent challenge with the same fungus. There was no sign of priming when using homologous and heterologous combinations of fungal strains for exposure and subsequent challenges at two time intervals. Hence, within the range of conditions tested, the immune response of this social insect to the fungal pathogen appears to lack memory and strain-specificity. These results show that immune priming is not ubiquitous across pathogens, hosts and conditions, possibly because of immune evasion by the pathogen or efficient social defences by the host. Public Library of Science 2012-04-16 /pmc/articles/PMC3327680/ /pubmed/22523588 http://dx.doi.org/10.1371/journal.pone.0035372 Text en Reber, Chapuisat. http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited. |
spellingShingle | Research Article Reber, Anabelle Chapuisat, Michel No Evidence for Immune Priming in Ants Exposed to a Fungal Pathogen |
title | No Evidence for Immune Priming in Ants Exposed to a Fungal Pathogen |
title_full | No Evidence for Immune Priming in Ants Exposed to a Fungal Pathogen |
title_fullStr | No Evidence for Immune Priming in Ants Exposed to a Fungal Pathogen |
title_full_unstemmed | No Evidence for Immune Priming in Ants Exposed to a Fungal Pathogen |
title_short | No Evidence for Immune Priming in Ants Exposed to a Fungal Pathogen |
title_sort | no evidence for immune priming in ants exposed to a fungal pathogen |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3327680/ https://www.ncbi.nlm.nih.gov/pubmed/22523588 http://dx.doi.org/10.1371/journal.pone.0035372 |
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