Synergistic Effect of SRY and Its Direct Target, WDR5, on Sox9 Expression

SRY is a sex-determining gene that encodes a transcription factor, which triggers male development in most mammals. The molecular mechanism of SRY action in testis determination is, however, poorly understood. In this study, we demonstrate that WDR5, which encodes a WD-40 repeat protein, is a direct...

Descripción completa

Detalles Bibliográficos
Autores principales: Xu, Zhen, Gao, Xinxing, He, Yinghong, Ju, Junyi, Zhang, Miaomiao, Liu, Ronghua, Wu, Yupeng, Ma, Chunyan, Ma, Chi, Lin, Zhaoyu, Huang, Xingxu, Zhao, Quan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3327683/
https://www.ncbi.nlm.nih.gov/pubmed/22523547
http://dx.doi.org/10.1371/journal.pone.0034327

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3327683/
https://www.ncbi.nlm.nih.gov/pubmed/22523547
http://dx.doi.org/10.1371/journal.pone.0034327

Ejemplares similares