Estimating the proportion of variation in susceptibility to schizophrenia captured by common SNPs

Schizophrenia is a complex disorder caused by both genetic and environmental factors. Using 9,087 cases, 12,171 controls and 915,354 imputed SNPs from the Psychiatric GWA Consortium for schizophrenia (PGC-SCZ) we estimate that 23% (s.e. 1%) of variation in liability to schizophrenia is captured by S...

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Detalles Bibliográficos
Autores principales: Lee, S Hong, DeCandia, Teresa R, Ripke, Stephan, Yang, Jian, Sullivan, Patrick F, Goddard, Michael E, Keller, Matthew C, Visscher, Peter M, Wray, Naomi R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3327879/
https://www.ncbi.nlm.nih.gov/pubmed/22344220
http://dx.doi.org/10.1038/ng.1108

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3327879/
https://www.ncbi.nlm.nih.gov/pubmed/22344220
http://dx.doi.org/10.1038/ng.1108

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