Erectile properties of the Rho-kinase inhibitor SAR407899 in diabetic animals and human isolated corpora cavernosa

BACKGROUND: RhoA-Rho kinase complex contributes to keep the cavernosus smooth muscle contracted and its inhibition is considered a potential strategy for the therapy of erectile dysfunction (ED). METHODS: We compared the effects of SAR407899, the Rho-kinase inhibitor Y-27632 and the PDE5 inhibitor s...

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Detalles Bibliográficos
Autores principales: Guagnini, Fabio, Ferazzini, Mara, Grasso, Marco, Blanco, Salvatore, Croci, Tiziano
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3328245/
https://www.ncbi.nlm.nih.gov/pubmed/22444253
http://dx.doi.org/10.1186/1479-5876-10-59

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3328245/
https://www.ncbi.nlm.nih.gov/pubmed/22444253
http://dx.doi.org/10.1186/1479-5876-10-59

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