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Acetylcholinesterase inhibition ameliorates deficits in motivational drive

BACKGROUND: Apathy is frequently observed in numerous neurological disorders, including Alzheimer's and Parkinson's, as well as neuropsychiatric disorders including schizophrenia. Apathy is defined as a lack of motivation characterized by diminished goal-oriented behavior and self-initiate...

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Detalles Bibliográficos
Autores principales: Martinowich, Keri, Cardinale, Kathleen M, Schloesser, Robert J, Hsu, Michael, Greig, Nigel H, Manji, Husseini K
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3328273/
https://www.ncbi.nlm.nih.gov/pubmed/22433906
http://dx.doi.org/10.1186/1744-9081-8-15