Cargando…
Most British Surgeons Would Consider Using a Tissue-Engineered Anterior Cruciate Ligament: A Questionnaire Study
Donor site morbidity, poor graft site integration, and incorrect mechanical performance are all common problems associated with autografts for anterior cruciate ligament (ACL) reconstructions. A tissue-engineered (TE) ligament has the potential to overcome these problems. We produced an online quest...
Autores principales: | , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2012
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3328275/ https://www.ncbi.nlm.nih.gov/pubmed/22567023 http://dx.doi.org/10.1155/2012/303724 |
_version_ | 1782229718482812928 |
---|---|
author | Rathbone, Sarah Maffulli, Nicola Cartmell, Sarah H. |
author_facet | Rathbone, Sarah Maffulli, Nicola Cartmell, Sarah H. |
author_sort | Rathbone, Sarah |
collection | PubMed |
description | Donor site morbidity, poor graft site integration, and incorrect mechanical performance are all common problems associated with autografts for anterior cruciate ligament (ACL) reconstructions. A tissue-engineered (TE) ligament has the potential to overcome these problems. We produced an online questionnaire relating to tissue engineering of the ACL to obtain input from practising clinicians who currently manage these injuries. 300 British orthopaedic surgeons specialising in knee surgery and soft tissue injury were invited to participate. 86% of surgeons would consider using a TE ACL if it were an option, provided that it showed biological and mechanical success, if it significantly improved the patient satisfaction (63%) or shortened surgical time (62%). 76% felt that using a TE ACL would be more appropriate than a patellar tendon, hamstring, or quadriceps autograft. Overall, most surgeons would be prepared to use a TE ACL if it were an improvement over the current techniques. |
format | Online Article Text |
id | pubmed-3328275 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2012 |
publisher | Hindawi Publishing Corporation |
record_format | MEDLINE/PubMed |
spelling | pubmed-33282752012-05-07 Most British Surgeons Would Consider Using a Tissue-Engineered Anterior Cruciate Ligament: A Questionnaire Study Rathbone, Sarah Maffulli, Nicola Cartmell, Sarah H. Stem Cells Int Review Article Donor site morbidity, poor graft site integration, and incorrect mechanical performance are all common problems associated with autografts for anterior cruciate ligament (ACL) reconstructions. A tissue-engineered (TE) ligament has the potential to overcome these problems. We produced an online questionnaire relating to tissue engineering of the ACL to obtain input from practising clinicians who currently manage these injuries. 300 British orthopaedic surgeons specialising in knee surgery and soft tissue injury were invited to participate. 86% of surgeons would consider using a TE ACL if it were an option, provided that it showed biological and mechanical success, if it significantly improved the patient satisfaction (63%) or shortened surgical time (62%). 76% felt that using a TE ACL would be more appropriate than a patellar tendon, hamstring, or quadriceps autograft. Overall, most surgeons would be prepared to use a TE ACL if it were an improvement over the current techniques. Hindawi Publishing Corporation 2012 2012-02-26 /pmc/articles/PMC3328275/ /pubmed/22567023 http://dx.doi.org/10.1155/2012/303724 Text en Copyright © 2012 Sarah Rathbone et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Review Article Rathbone, Sarah Maffulli, Nicola Cartmell, Sarah H. Most British Surgeons Would Consider Using a Tissue-Engineered Anterior Cruciate Ligament: A Questionnaire Study |
title | Most British Surgeons Would Consider Using a Tissue-Engineered Anterior Cruciate Ligament: A Questionnaire Study |
title_full | Most British Surgeons Would Consider Using a Tissue-Engineered Anterior Cruciate Ligament: A Questionnaire Study |
title_fullStr | Most British Surgeons Would Consider Using a Tissue-Engineered Anterior Cruciate Ligament: A Questionnaire Study |
title_full_unstemmed | Most British Surgeons Would Consider Using a Tissue-Engineered Anterior Cruciate Ligament: A Questionnaire Study |
title_short | Most British Surgeons Would Consider Using a Tissue-Engineered Anterior Cruciate Ligament: A Questionnaire Study |
title_sort | most british surgeons would consider using a tissue-engineered anterior cruciate ligament: a questionnaire study |
topic | Review Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3328275/ https://www.ncbi.nlm.nih.gov/pubmed/22567023 http://dx.doi.org/10.1155/2012/303724 |
work_keys_str_mv | AT rathbonesarah mostbritishsurgeonswouldconsiderusingatissueengineeredanteriorcruciateligamentaquestionnairestudy AT maffullinicola mostbritishsurgeonswouldconsiderusingatissueengineeredanteriorcruciateligamentaquestionnairestudy AT cartmellsarahh mostbritishsurgeonswouldconsiderusingatissueengineeredanteriorcruciateligamentaquestionnairestudy |