Cargando…

Most British Surgeons Would Consider Using a Tissue-Engineered Anterior Cruciate Ligament: A Questionnaire Study

Donor site morbidity, poor graft site integration, and incorrect mechanical performance are all common problems associated with autografts for anterior cruciate ligament (ACL) reconstructions. A tissue-engineered (TE) ligament has the potential to overcome these problems. We produced an online quest...

Descripción completa

Detalles Bibliográficos
Autores principales: Rathbone, Sarah, Maffulli, Nicola, Cartmell, Sarah H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3328275/
https://www.ncbi.nlm.nih.gov/pubmed/22567023
http://dx.doi.org/10.1155/2012/303724
_version_ 1782229718482812928
author Rathbone, Sarah
Maffulli, Nicola
Cartmell, Sarah H.
author_facet Rathbone, Sarah
Maffulli, Nicola
Cartmell, Sarah H.
author_sort Rathbone, Sarah
collection PubMed
description Donor site morbidity, poor graft site integration, and incorrect mechanical performance are all common problems associated with autografts for anterior cruciate ligament (ACL) reconstructions. A tissue-engineered (TE) ligament has the potential to overcome these problems. We produced an online questionnaire relating to tissue engineering of the ACL to obtain input from practising clinicians who currently manage these injuries. 300 British orthopaedic surgeons specialising in knee surgery and soft tissue injury were invited to participate. 86% of surgeons would consider using a TE ACL if it were an option, provided that it showed biological and mechanical success, if it significantly improved the patient satisfaction (63%) or shortened surgical time (62%). 76% felt that using a TE ACL would be more appropriate than a patellar tendon, hamstring, or quadriceps autograft. Overall, most surgeons would be prepared to use a TE ACL if it were an improvement over the current techniques.
format Online
Article
Text
id pubmed-3328275
institution National Center for Biotechnology Information
language English
publishDate 2012
publisher Hindawi Publishing Corporation
record_format MEDLINE/PubMed
spelling pubmed-33282752012-05-07 Most British Surgeons Would Consider Using a Tissue-Engineered Anterior Cruciate Ligament: A Questionnaire Study Rathbone, Sarah Maffulli, Nicola Cartmell, Sarah H. Stem Cells Int Review Article Donor site morbidity, poor graft site integration, and incorrect mechanical performance are all common problems associated with autografts for anterior cruciate ligament (ACL) reconstructions. A tissue-engineered (TE) ligament has the potential to overcome these problems. We produced an online questionnaire relating to tissue engineering of the ACL to obtain input from practising clinicians who currently manage these injuries. 300 British orthopaedic surgeons specialising in knee surgery and soft tissue injury were invited to participate. 86% of surgeons would consider using a TE ACL if it were an option, provided that it showed biological and mechanical success, if it significantly improved the patient satisfaction (63%) or shortened surgical time (62%). 76% felt that using a TE ACL would be more appropriate than a patellar tendon, hamstring, or quadriceps autograft. Overall, most surgeons would be prepared to use a TE ACL if it were an improvement over the current techniques. Hindawi Publishing Corporation 2012 2012-02-26 /pmc/articles/PMC3328275/ /pubmed/22567023 http://dx.doi.org/10.1155/2012/303724 Text en Copyright © 2012 Sarah Rathbone et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Review Article
Rathbone, Sarah
Maffulli, Nicola
Cartmell, Sarah H.
Most British Surgeons Would Consider Using a Tissue-Engineered Anterior Cruciate Ligament: A Questionnaire Study
title Most British Surgeons Would Consider Using a Tissue-Engineered Anterior Cruciate Ligament: A Questionnaire Study
title_full Most British Surgeons Would Consider Using a Tissue-Engineered Anterior Cruciate Ligament: A Questionnaire Study
title_fullStr Most British Surgeons Would Consider Using a Tissue-Engineered Anterior Cruciate Ligament: A Questionnaire Study
title_full_unstemmed Most British Surgeons Would Consider Using a Tissue-Engineered Anterior Cruciate Ligament: A Questionnaire Study
title_short Most British Surgeons Would Consider Using a Tissue-Engineered Anterior Cruciate Ligament: A Questionnaire Study
title_sort most british surgeons would consider using a tissue-engineered anterior cruciate ligament: a questionnaire study
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3328275/
https://www.ncbi.nlm.nih.gov/pubmed/22567023
http://dx.doi.org/10.1155/2012/303724
work_keys_str_mv AT rathbonesarah mostbritishsurgeonswouldconsiderusingatissueengineeredanteriorcruciateligamentaquestionnairestudy
AT maffullinicola mostbritishsurgeonswouldconsiderusingatissueengineeredanteriorcruciateligamentaquestionnairestudy
AT cartmellsarahh mostbritishsurgeonswouldconsiderusingatissueengineeredanteriorcruciateligamentaquestionnairestudy