The hypoxia imaging agent Cu(II)(atsm) is neuroprotective and improves motor and cognitive functions in multiple animal models of Parkinson’s disease

Parkinson’s disease (PD) is a progressive, chronic disease characterized by dyskinesia, rigidity, instability, and tremors. The disease is defined by the presence of Lewy bodies, which primarily consist of aggregated α-synuclein protein, and is accompanied by the loss of monoaminergic neurons. Curre...

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Detalles Bibliográficos
Autores principales: Hung, Lin W., Villemagne, Victor L., Cheng, Lesley, Sherratt, Nicki A., Ayton, Scott, White, Anthony R., Crouch, Peter J., Lim, SinChun, Leong, Su Ling, Wilkins, Simon, George, Jessica, Roberts, Blaine R., Pham, Chi L.L., Liu, Xiang, Chiu, Francis C.K., Shackleford, David M., Powell, Andrew K., Masters, Colin L., Bush, Ashley I., O’Keefe, Graeme, Culvenor, Janetta G., Cappai, Roberto, Cherny, Robert A., Donnelly, Paul S., Hill, Andrew F., Finkelstein, David I., Barnham, Kevin J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3328361/
https://www.ncbi.nlm.nih.gov/pubmed/22473957
http://dx.doi.org/10.1084/jem.20112285

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