Naive T cells are dispensable for memory CD4(+) T cell homeostasis in progressive simian immunodeficiency virus infection

The development of AIDS in chronic HIV/simian immunodeficiency virus (SIV) infection has been closely linked to progressive failure of CD4(+) memory T cell (T(M)) homeostasis. CD4(+) naive T cells (T(N)) also decline in these infections, but their contribution to disease progression is less clear. W...

Descripción completa

Detalles Bibliográficos
Autores principales: Okoye, Afam A., Rohankhedkar, Mukta, Abana, Chike, Pattenn, Audrie, Reyes, Matthew, Pexton, Christopher, Lum, Richard, Sylwester, Andrew, Planer, Shannon L., Legasse, Alfred, Park, Byung S., Piatak, Michael, Lifson, Jeffrey D., Axthelm, Michael K., Picker, Louis J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2012
Materias:
Brief Definitive Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3328373/
https://www.ncbi.nlm.nih.gov/pubmed/22451717
http://dx.doi.org/10.1084/jem.20112071

Ejemplares similares

Ejemplares similares