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MCAK activity at microtubule tips regulates spindle microtubule length to promote robust kinetochore attachment
Mitotic centromere-associated kinesin (MCAK) is a microtubule-depolymerizing kinesin-13 member that can track with polymerizing microtubule tips (hereafter referred to as tip tracking) during both interphase and mitosis. MCAK tracks with microtubule tips by binding to end-binding proteins (EBs) thro...
Autores principales: | Domnitz, Sarah B., Wagenbach, Michael, Decarreau, Justin, Wordeman, Linda |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3328376/ https://www.ncbi.nlm.nih.gov/pubmed/22492725 http://dx.doi.org/10.1083/jcb.201108147 |
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