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The Arp2/3 complex is required for lamellipodia extension and directional fibroblast cell migration
The Arp2/3 complex nucleates the formation of the dendritic actin network at the leading edge of motile cells, but it is still unclear if the Arp2/3 complex plays a critical role in lamellipodia protrusion and cell motility. Here, we differentiated motile fibroblast cells from isogenic mouse embryon...
Autores principales: | Suraneni, Praveen, Rubinstein, Boris, Unruh, Jay R., Durnin, Michael, Hanein, Dorit, Li, Rong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3328382/ https://www.ncbi.nlm.nih.gov/pubmed/22492726 http://dx.doi.org/10.1083/jcb.201112113 |
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