BRCA1 regulates microRNA biogenesis via the DROSHA microprocessor complex

MicroRNAs (miRNAs) are noncoding RNAs that function as key posttranscriptional regulators of gene expression. miRNA maturation is controlled by the DROSHA microprocessor complex. However, the detailed mechanism of miRNA biogenesis remains unclear. We show that the tumor suppressor breast cancer 1 (B...

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Detalles Bibliográficos
Autores principales: Kawai, Shinji, Amano, Atsuo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2012
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3328391/
https://www.ncbi.nlm.nih.gov/pubmed/22492723
http://dx.doi.org/10.1083/jcb.201110008

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3328391/
https://www.ncbi.nlm.nih.gov/pubmed/22492723
http://dx.doi.org/10.1083/jcb.201110008

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