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Role of the CCAAT-Binding Protein NFY in SCA17 Pathogenesis
Spinocerebellar ataxia 17 (SCA17) is caused by expansion of the polyglutamine (polyQ) tract in human TATA-box binding protein (TBP) that is ubiquitously expressed in both central nervous system and peripheral tissues. The spectrum of SCA17 clinical presentation is broad. The precise pathogenic mecha...
Autores principales: | Lee, Li-Ching, Chen, Chiung-Mei, Wang, Hao-Chun, Hsieh, Hsiao-Han, Chiu, I-Sheng, Su, Ming-Tsan, Hsieh-Li, Hsiu-Mei, Wu, Chung-Hsin, Lee, Guan-Chiun, Lee-Chen, Guey-Jen, Lin, Jung-Yaw |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3328435/ https://www.ncbi.nlm.nih.gov/pubmed/22530004 http://dx.doi.org/10.1371/journal.pone.0035302 |
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