Cargando…

Geographic and Racial Variation in Premature Mortality in the U.S.: Analyzing the Disparities

Life expectancy at birth, estimated from United States period life tables, has been shown to vary systematically and widely by region and race. We use the same tables to estimate the probability of survival from birth to age 70 (S(70)), a measure of mortality more sensitive to disparities and more r...

Descripción completa

Detalles Bibliográficos
Autores principales: Cullen, Mark R., Cummins, Clint, Fuchs, Victor R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3328498/
https://www.ncbi.nlm.nih.gov/pubmed/22529892
http://dx.doi.org/10.1371/journal.pone.0032930
_version_ 1782229754632470528
author Cullen, Mark R.
Cummins, Clint
Fuchs, Victor R.
author_facet Cullen, Mark R.
Cummins, Clint
Fuchs, Victor R.
author_sort Cullen, Mark R.
collection PubMed
description Life expectancy at birth, estimated from United States period life tables, has been shown to vary systematically and widely by region and race. We use the same tables to estimate the probability of survival from birth to age 70 (S(70)), a measure of mortality more sensitive to disparities and more reliably calculated for small populations, to describe the variation and identify its sources in greater detail to assess the patterns of this variation. Examination of the unadjusted probability of S(70) for each US county with a sufficient population of whites and blacks reveals large geographic differences for each race-sex group. For example, white males born in the ten percent healthiest counties have a 77 percent probability of survival to age 70, but only a 61 percent chance if born in the ten percent least healthy counties. Similar geographical disparities face white women and blacks of each sex. Moreover, within each county, large differences in S(70) prevail between blacks and whites, on average 17 percentage points for men and 12 percentage points for women. In linear regressions for each race-sex group, nearly all of the geographic variation is accounted for by a common set of 22 socio-economic and environmental variables, selected for previously suspected impact on mortality; R(2) ranges from 0.86 for white males to 0.72 for black females. Analysis of black-white survival chances within each county reveals that the same variables account for most of the race gap in S(70) as well. When actual white male values for each explanatory variable are substituted for black in the black male prediction equation to assess the role explanatory variables play in the black-white survival difference, residual black-white differences at the county level shrink markedly to a mean of −2.4% (+/−2.4); for women the mean difference is −3.7% (+/−2.3).
format Online
Article
Text
id pubmed-3328498
institution National Center for Biotechnology Information
language English
publishDate 2012
publisher Public Library of Science
record_format MEDLINE/PubMed
spelling pubmed-33284982012-04-23 Geographic and Racial Variation in Premature Mortality in the U.S.: Analyzing the Disparities Cullen, Mark R. Cummins, Clint Fuchs, Victor R. PLoS One Research Article Life expectancy at birth, estimated from United States period life tables, has been shown to vary systematically and widely by region and race. We use the same tables to estimate the probability of survival from birth to age 70 (S(70)), a measure of mortality more sensitive to disparities and more reliably calculated for small populations, to describe the variation and identify its sources in greater detail to assess the patterns of this variation. Examination of the unadjusted probability of S(70) for each US county with a sufficient population of whites and blacks reveals large geographic differences for each race-sex group. For example, white males born in the ten percent healthiest counties have a 77 percent probability of survival to age 70, but only a 61 percent chance if born in the ten percent least healthy counties. Similar geographical disparities face white women and blacks of each sex. Moreover, within each county, large differences in S(70) prevail between blacks and whites, on average 17 percentage points for men and 12 percentage points for women. In linear regressions for each race-sex group, nearly all of the geographic variation is accounted for by a common set of 22 socio-economic and environmental variables, selected for previously suspected impact on mortality; R(2) ranges from 0.86 for white males to 0.72 for black females. Analysis of black-white survival chances within each county reveals that the same variables account for most of the race gap in S(70) as well. When actual white male values for each explanatory variable are substituted for black in the black male prediction equation to assess the role explanatory variables play in the black-white survival difference, residual black-white differences at the county level shrink markedly to a mean of −2.4% (+/−2.4); for women the mean difference is −3.7% (+/−2.3). Public Library of Science 2012-04-17 /pmc/articles/PMC3328498/ /pubmed/22529892 http://dx.doi.org/10.1371/journal.pone.0032930 Text en Cullen et al. http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.
spellingShingle Research Article
Cullen, Mark R.
Cummins, Clint
Fuchs, Victor R.
Geographic and Racial Variation in Premature Mortality in the U.S.: Analyzing the Disparities
title Geographic and Racial Variation in Premature Mortality in the U.S.: Analyzing the Disparities
title_full Geographic and Racial Variation in Premature Mortality in the U.S.: Analyzing the Disparities
title_fullStr Geographic and Racial Variation in Premature Mortality in the U.S.: Analyzing the Disparities
title_full_unstemmed Geographic and Racial Variation in Premature Mortality in the U.S.: Analyzing the Disparities
title_short Geographic and Racial Variation in Premature Mortality in the U.S.: Analyzing the Disparities
title_sort geographic and racial variation in premature mortality in the u.s.: analyzing the disparities
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3328498/
https://www.ncbi.nlm.nih.gov/pubmed/22529892
http://dx.doi.org/10.1371/journal.pone.0032930
work_keys_str_mv AT cullenmarkr geographicandracialvariationinprematuremortalityintheusanalyzingthedisparities
AT cumminsclint geographicandracialvariationinprematuremortalityintheusanalyzingthedisparities
AT fuchsvictorr geographicandracialvariationinprematuremortalityintheusanalyzingthedisparities