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Early Treatment With Olmesartan Prevents Juxtamedullary Glomerular Podocyte Injury and the Onset of Microalbuminuria in Type 2 Diabetic Rats

BACKGROUND: Studies were performed to determine if early treatment with an angiotensin II (Ang II) receptor blocker (ARB), olmesartan, prevents the onset of microalbuminuria by attenuating glomerular podocyte injury in Otsuka Long-Evans Tokushima Fatty (OLETF) rats with type 2 diabetes mellitus. MET...

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Detalles Bibliográficos
Autores principales: Sofue, Tadashi, Kiyomoto, Hideyasu, Kobori, Hiroyuki, Urushihara, Maki, Nishijima, Yoko, Kaifu, Kumiko, Hara, Taiga, Matsumoto, Sachiko, Ichimura, Atsuhiko, Ohsaki, Hiroyuki, Hitomi, Hirofumi, Kawachi, Hiroshi, Hayden, Melvin R., Whaley-Connell, Adam, Sowers, James R., Ito, Sadayoshi, Kohno, Masakazu, Nishiyama, Akira
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3328599/
https://www.ncbi.nlm.nih.gov/pubmed/22318512
http://dx.doi.org/10.1038/ajh.2012.1

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