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Early Treatment With Olmesartan Prevents Juxtamedullary Glomerular Podocyte Injury and the Onset of Microalbuminuria in Type 2 Diabetic Rats
BACKGROUND: Studies were performed to determine if early treatment with an angiotensin II (Ang II) receptor blocker (ARB), olmesartan, prevents the onset of microalbuminuria by attenuating glomerular podocyte injury in Otsuka Long-Evans Tokushima Fatty (OLETF) rats with type 2 diabetes mellitus. MET...
Autores principales: | Sofue, Tadashi, Kiyomoto, Hideyasu, Kobori, Hiroyuki, Urushihara, Maki, Nishijima, Yoko, Kaifu, Kumiko, Hara, Taiga, Matsumoto, Sachiko, Ichimura, Atsuhiko, Ohsaki, Hiroyuki, Hitomi, Hirofumi, Kawachi, Hiroshi, Hayden, Melvin R., Whaley-Connell, Adam, Sowers, James R., Ito, Sadayoshi, Kohno, Masakazu, Nishiyama, Akira |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3328599/ https://www.ncbi.nlm.nih.gov/pubmed/22318512 http://dx.doi.org/10.1038/ajh.2012.1 |
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