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Structural characterization of angiotensin I-converting enzyme in complex with a selenium analogue of captopril

Human somatic angiotensin I-converting enzyme (ACE), a zinc-dependent dipeptidyl carboxypeptidase, is central to the regulation of the renin–angiotensin aldosterone system. It is a well-known target for combating hypertension and related cardiovascular diseases. In a recent study by Bhuyan and Muges...

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Detalles Bibliográficos
Autores principales: Akif, Mohd, Masuyer, Geoffrey, Schwager, Sylva L U, Bhuyan, Bhaskar J, Mugesh, Govindasamy, Isaac, R Elwyn, Sturrock, Edward D, Acharya, K Ravi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3328747/
https://www.ncbi.nlm.nih.gov/pubmed/21810173
http://dx.doi.org/10.1111/j.1742-4658.2011.08276.x