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Structural characterization of angiotensin I-converting enzyme in complex with a selenium analogue of captopril
Human somatic angiotensin I-converting enzyme (ACE), a zinc-dependent dipeptidyl carboxypeptidase, is central to the regulation of the renin–angiotensin aldosterone system. It is a well-known target for combating hypertension and related cardiovascular diseases. In a recent study by Bhuyan and Muges...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Blackwell Publishing Ltd
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3328747/ https://www.ncbi.nlm.nih.gov/pubmed/21810173 http://dx.doi.org/10.1111/j.1742-4658.2011.08276.x |