Novel Assays of Thrombogenic Pathogenicity in the Antiphospholipid Syndrome Based on the Detection of Molecular Oxidative Modification of the Major Autoantigen β(2)-Glycoprotein I

OBJECTIVE: Beta-2-glycoprotein I (β(2)GPI) constitutes the major autoantigen in the antiphospholipid syndrome (APS), a common acquired cause of arterial and venous thrombosis. We recently described the novel observation that β(2)GPI may exist in healthy individuals in a free thiol (biochemically red...

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Detalles Bibliográficos
Autores principales: Ioannou, Yiannis, Zhang, Jing-Yun, Qi, Miao, Gao, Lu, Qi, Jian Cheng, Yu, De-Min, Lau, Herman, Sturgess, Allan D, Vlachoyiannopoulos, Panayiotis G, Moutsopoulos, Haralampos M, Rahman, Anisur, Pericleous, Charis, Atsumi, Tatsuya, Koike, Takao, Heritier, Stephane, Giannakopoulos, Bill, Krilis, Steven A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wiley Subscription Services, Inc., A Wiley Company 2011
Materias:
Systemic Lupus Erythematosus
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3328749/
https://www.ncbi.nlm.nih.gov/pubmed/21618459
http://dx.doi.org/10.1002/art.30383

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