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IL-1RI (interleukin-1 receptor type I) signalling is essential for host defence and hemichannel activity during acute central nervous system bacterial infection

Staphylococcus aureus is a common aetiological agent of bacterial brain abscesses. We have previously established that a considerable IL-1 (interleukin-1) response is elicited immediately following S. aureus infection, where the cytokine can exert pleiotropic effects on glial activation and blood–br...

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Detalles Bibliográficos
Autores principales:	Xiong, Juan, Burkovetskaya, Maria, Karpuk, Nikolay, Kielian, Tammy
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Neurochemistry 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3328864/ https://www.ncbi.nlm.nih.gov/pubmed/22414156 http://dx.doi.org/10.1042/AN20120008

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