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Sickle Cell Disease Activates Peripheral Blood Mononuclear Cells to Induce Cathepsins K and V Activity in Endothelial Cells

Sickle cell disease is a genetic disease that increases systemic inflammation as well as the risk of pediatric strokes, but links between sickle-induced inflammation and arterial remodeling are not clear. Cathepsins are powerful elastases and collagenases secreted by endothelial cells and monocyte-d...

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Detalles Bibliográficos
Autores principales:	Keegan, Philip M., Surapaneni, Sindhuja, Platt, Manu O.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi Publishing Corporation 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3328887/ https://www.ncbi.nlm.nih.gov/pubmed/22550569 http://dx.doi.org/10.1155/2012/201781

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