Decreased Levofloxacin Susceptibility in Haemophilus influenzae in Children, Hong Kong

Among 563 strains of Haemophilus influenzae from young children in Hong Kong, 5 (0.9%) had decreased susceptibility to quinolones. The five strains had a Ser-84-Lys or Asp-88-Asn substitution in GyrA. Pulsed-field gel electrophoresis showed that the isolates are genetically diverse.

Detalles Bibliográficos
Autores principales: Ho, Pak-Leung, Chow, Kin Hung, Mak, Gannon C., Tsang, Kenneth W., Lau, Yu Lung, Ho, Alex Y., Lai, Eileen L., Chiu, Susan S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Centers for Disease Control and Prevention 2004
Materias:
Dispatch
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3328986/
https://www.ncbi.nlm.nih.gov/pubmed/15550208
http://dx.doi.org/10.3201/eid1011.040055
Descripción
Sumario:Among 563 strains of Haemophilus influenzae from young children in Hong Kong, 5 (0.9%) had decreased susceptibility to quinolones. The five strains had a Ser-84-Lys or Asp-88-Asn substitution in GyrA. Pulsed-field gel electrophoresis showed that the isolates are genetically diverse.

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