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Decreased Levofloxacin Susceptibility in Haemophilus influenzae in Children, Hong Kong

Among 563 strains of Haemophilus influenzae from young children in Hong Kong, 5 (0.9%) had decreased susceptibility to quinolones. The five strains had a Ser-84-Lys or Asp-88-Asn substitution in GyrA. Pulsed-field gel electrophoresis showed that the isolates are genetically diverse.

Detalles Bibliográficos
Autores principales: Ho, Pak-Leung, Chow, Kin Hung, Mak, Gannon C., Tsang, Kenneth W., Lau, Yu Lung, Ho, Alex Y., Lai, Eileen L., Chiu, Susan S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Centers for Disease Control and Prevention 2004
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3328986/
https://www.ncbi.nlm.nih.gov/pubmed/15550208
http://dx.doi.org/10.3201/eid1011.040055
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author Ho, Pak-Leung
Chow, Kin Hung
Mak, Gannon C.
Tsang, Kenneth W.
Lau, Yu Lung
Ho, Alex Y.
Lai, Eileen L.
Chiu, Susan S.
author_facet Ho, Pak-Leung
Chow, Kin Hung
Mak, Gannon C.
Tsang, Kenneth W.
Lau, Yu Lung
Ho, Alex Y.
Lai, Eileen L.
Chiu, Susan S.
author_sort Ho, Pak-Leung
collection PubMed
description Among 563 strains of Haemophilus influenzae from young children in Hong Kong, 5 (0.9%) had decreased susceptibility to quinolones. The five strains had a Ser-84-Lys or Asp-88-Asn substitution in GyrA. Pulsed-field gel electrophoresis showed that the isolates are genetically diverse.
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spelling pubmed-33289862012-04-18 Decreased Levofloxacin Susceptibility in Haemophilus influenzae in Children, Hong Kong Ho, Pak-Leung Chow, Kin Hung Mak, Gannon C. Tsang, Kenneth W. Lau, Yu Lung Ho, Alex Y. Lai, Eileen L. Chiu, Susan S. Emerg Infect Dis Dispatch Among 563 strains of Haemophilus influenzae from young children in Hong Kong, 5 (0.9%) had decreased susceptibility to quinolones. The five strains had a Ser-84-Lys or Asp-88-Asn substitution in GyrA. Pulsed-field gel electrophoresis showed that the isolates are genetically diverse. Centers for Disease Control and Prevention 2004-11 /pmc/articles/PMC3328986/ /pubmed/15550208 http://dx.doi.org/10.3201/eid1011.040055 Text en https://creativecommons.org/licenses/by/4.0/This is a publication of the U.S. Government. This publication is in the public domain and is therefore without copyright. All text from this work may be reprinted freely. Use of these materials should be properly cited.
spellingShingle Dispatch
Ho, Pak-Leung
Chow, Kin Hung
Mak, Gannon C.
Tsang, Kenneth W.
Lau, Yu Lung
Ho, Alex Y.
Lai, Eileen L.
Chiu, Susan S.
Decreased Levofloxacin Susceptibility in Haemophilus influenzae in Children, Hong Kong
title Decreased Levofloxacin Susceptibility in Haemophilus influenzae in Children, Hong Kong
title_full Decreased Levofloxacin Susceptibility in Haemophilus influenzae in Children, Hong Kong
title_fullStr Decreased Levofloxacin Susceptibility in Haemophilus influenzae in Children, Hong Kong
title_full_unstemmed Decreased Levofloxacin Susceptibility in Haemophilus influenzae in Children, Hong Kong
title_short Decreased Levofloxacin Susceptibility in Haemophilus influenzae in Children, Hong Kong
title_sort decreased levofloxacin susceptibility in haemophilus influenzae in children, hong kong
topic Dispatch
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3328986/
https://www.ncbi.nlm.nih.gov/pubmed/15550208
http://dx.doi.org/10.3201/eid1011.040055
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