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Hydatidiform mole in Jos, Nigeria

BACKGROUND: Hydatidiform mole is a relatively common gynecological problem which could present like spontaneous abortion, one of the commonest gynecological emergencies. It has the propensity to become malignant but can easily be identified and treated. The aim of this study was to determine the dem...

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Autores principales: Ocheke, Amaka N., Musa, Jonah, Uamai, Alexander O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3329089/
https://www.ncbi.nlm.nih.gov/pubmed/22529502
http://dx.doi.org/10.4103/0300-1652.93792
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author Ocheke, Amaka N.
Musa, Jonah
Uamai, Alexander O.
author_facet Ocheke, Amaka N.
Musa, Jonah
Uamai, Alexander O.
author_sort Ocheke, Amaka N.
collection PubMed
description BACKGROUND: Hydatidiform mole is a relatively common gynecological problem which could present like spontaneous abortion, one of the commonest gynecological emergencies. It has the propensity to become malignant but can easily be identified and treated. The aim of this study was to determine the demographics, clinical features, treatment options and outcome of patients with hydatidiform mole in our environment. MATERIALS AND METHODS: This was a retrospective review of all the cases of hydatidiform mole seen at the Jos University Teaching Hospital (JUTH), Jos, Nigeria over a 5-year period. RESULTS: There were 34 cases of hydatidiform mole giving an incidence of 1 in 357 deliveries. However only 25 case notes were available for analysis and the mean age of patients was 28±3 years. Vaginal bleeding (92%), honeycomb appearance on ultrasound scan (84%), and passage of vesicles (60%) were the most common clinical findings while suction curettage was the mode of treatment for all the patients in this study. Twenty-eight percent of cases were confirmed by histology. No patient came for follow-up after the third month of diagnosis. Twenty percent of the patients booked for antenatal care within 9 months of diagnosis while 12% of patients presented as gynecological emergencies with features of malignant disease within six months of diagnosis. CONCLUSION: Hydatidiform mole is common in Jos, North Central Nigeria, and presents most commonly with vaginal bleeding with over 10% becoming malignant. Hence all patients who present with vaginal bleeding should be screened for HM. None of the patients completed the recommended duration of follow-up and only about ¼ had histology reports. Concerted efforts need to be made to address the challenges of patients adhering to recommended follow-up protocols and having to pay first before investigations are done.
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spelling pubmed-33290892012-04-23 Hydatidiform mole in Jos, Nigeria Ocheke, Amaka N. Musa, Jonah Uamai, Alexander O. Niger Med J Original Article BACKGROUND: Hydatidiform mole is a relatively common gynecological problem which could present like spontaneous abortion, one of the commonest gynecological emergencies. It has the propensity to become malignant but can easily be identified and treated. The aim of this study was to determine the demographics, clinical features, treatment options and outcome of patients with hydatidiform mole in our environment. MATERIALS AND METHODS: This was a retrospective review of all the cases of hydatidiform mole seen at the Jos University Teaching Hospital (JUTH), Jos, Nigeria over a 5-year period. RESULTS: There were 34 cases of hydatidiform mole giving an incidence of 1 in 357 deliveries. However only 25 case notes were available for analysis and the mean age of patients was 28±3 years. Vaginal bleeding (92%), honeycomb appearance on ultrasound scan (84%), and passage of vesicles (60%) were the most common clinical findings while suction curettage was the mode of treatment for all the patients in this study. Twenty-eight percent of cases were confirmed by histology. No patient came for follow-up after the third month of diagnosis. Twenty percent of the patients booked for antenatal care within 9 months of diagnosis while 12% of patients presented as gynecological emergencies with features of malignant disease within six months of diagnosis. CONCLUSION: Hydatidiform mole is common in Jos, North Central Nigeria, and presents most commonly with vaginal bleeding with over 10% becoming malignant. Hence all patients who present with vaginal bleeding should be screened for HM. None of the patients completed the recommended duration of follow-up and only about ¼ had histology reports. Concerted efforts need to be made to address the challenges of patients adhering to recommended follow-up protocols and having to pay first before investigations are done. Medknow Publications & Media Pvt Ltd 2011 /pmc/articles/PMC3329089/ /pubmed/22529502 http://dx.doi.org/10.4103/0300-1652.93792 Text en Copyright: © Nigerian Medical Journal http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Article
Ocheke, Amaka N.
Musa, Jonah
Uamai, Alexander O.
Hydatidiform mole in Jos, Nigeria
title Hydatidiform mole in Jos, Nigeria
title_full Hydatidiform mole in Jos, Nigeria
title_fullStr Hydatidiform mole in Jos, Nigeria
title_full_unstemmed Hydatidiform mole in Jos, Nigeria
title_short Hydatidiform mole in Jos, Nigeria
title_sort hydatidiform mole in jos, nigeria
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3329089/
https://www.ncbi.nlm.nih.gov/pubmed/22529502
http://dx.doi.org/10.4103/0300-1652.93792
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