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Donor blood procurement and the risk of transfusion transmissible viral infections in a tertiary health facility in South-South Nigeria

BACKGROUND: Blood and blood products are scarce commodities. The demand often outweighs the supply. This study is directed at investigating the blood procurement sources and the risk of viral transfusion transmissible infection. MATERIALS AND METHODS: The records of the blood transfusion unit of a t...

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Autores principales: Nwogoh, Benedict, Ikpomwen, O. D., Isoa, E. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3329090/
https://www.ncbi.nlm.nih.gov/pubmed/22529503
http://dx.doi.org/10.4103/0300-1652.93793
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author Nwogoh, Benedict
Ikpomwen, O. D.
Isoa, E. M.
author_facet Nwogoh, Benedict
Ikpomwen, O. D.
Isoa, E. M.
author_sort Nwogoh, Benedict
collection PubMed
description BACKGROUND: Blood and blood products are scarce commodities. The demand often outweighs the supply. This study is directed at investigating the blood procurement sources and the risk of viral transfusion transmissible infection. MATERIALS AND METHODS: The records of the blood transfusion unit of a tertiary health facility in south-south Nigeria were studied. The procurement and screening records from 1 January to 31 December 2009 were analyzed. RESULTS: 7,552 donor records were analyzed, 6,931 were commercial donor and 621 replacement donors. 891 commercial donors were infected, 500 (7.2%) were HIV positive, 323 (4.7%) HBV positive, 42 (0.6%) had HIV and HBV co-infection, while 28 (0.4%) were HCV positive. Twenty-three replacement donors were infected, 16 (2.6%) were HIV positive, 6 (1%) were HBV positive, while 1 (0.2%) were HCV positive. None of the replacement donors had co-infection. The risk of infection was significantly higher with commercial donor procurement (X2=45.07, P<0.001, OD=3.845). CONCLUSION: Commercial blood donors are still the major source of blood to the hospital and they also have the highest prevalence of transfusion transmissible viral infections in this region thus constitute a major risk transmitting infections to potential recipients.
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spelling pubmed-33290902012-04-23 Donor blood procurement and the risk of transfusion transmissible viral infections in a tertiary health facility in South-South Nigeria Nwogoh, Benedict Ikpomwen, O. D. Isoa, E. M. Niger Med J Original Article BACKGROUND: Blood and blood products are scarce commodities. The demand often outweighs the supply. This study is directed at investigating the blood procurement sources and the risk of viral transfusion transmissible infection. MATERIALS AND METHODS: The records of the blood transfusion unit of a tertiary health facility in south-south Nigeria were studied. The procurement and screening records from 1 January to 31 December 2009 were analyzed. RESULTS: 7,552 donor records were analyzed, 6,931 were commercial donor and 621 replacement donors. 891 commercial donors were infected, 500 (7.2%) were HIV positive, 323 (4.7%) HBV positive, 42 (0.6%) had HIV and HBV co-infection, while 28 (0.4%) were HCV positive. Twenty-three replacement donors were infected, 16 (2.6%) were HIV positive, 6 (1%) were HBV positive, while 1 (0.2%) were HCV positive. None of the replacement donors had co-infection. The risk of infection was significantly higher with commercial donor procurement (X2=45.07, P<0.001, OD=3.845). CONCLUSION: Commercial blood donors are still the major source of blood to the hospital and they also have the highest prevalence of transfusion transmissible viral infections in this region thus constitute a major risk transmitting infections to potential recipients. Medknow Publications & Media Pvt Ltd 2011 /pmc/articles/PMC3329090/ /pubmed/22529503 http://dx.doi.org/10.4103/0300-1652.93793 Text en Copyright: © Nigerian Medical Journal http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Article
Nwogoh, Benedict
Ikpomwen, O. D.
Isoa, E. M.
Donor blood procurement and the risk of transfusion transmissible viral infections in a tertiary health facility in South-South Nigeria
title Donor blood procurement and the risk of transfusion transmissible viral infections in a tertiary health facility in South-South Nigeria
title_full Donor blood procurement and the risk of transfusion transmissible viral infections in a tertiary health facility in South-South Nigeria
title_fullStr Donor blood procurement and the risk of transfusion transmissible viral infections in a tertiary health facility in South-South Nigeria
title_full_unstemmed Donor blood procurement and the risk of transfusion transmissible viral infections in a tertiary health facility in South-South Nigeria
title_short Donor blood procurement and the risk of transfusion transmissible viral infections in a tertiary health facility in South-South Nigeria
title_sort donor blood procurement and the risk of transfusion transmissible viral infections in a tertiary health facility in south-south nigeria
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3329090/
https://www.ncbi.nlm.nih.gov/pubmed/22529503
http://dx.doi.org/10.4103/0300-1652.93793
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