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Transancestral mapping of the MHC region in systemic lupus erythematosus identifies new independent and interacting loci at MSH5, HLA-DPB1 and HLA-G
OBJECTIVES: Systemic lupus erythematosus (SLE) is a chronic multisystem genetically complex autoimmune disease characterised by the production of autoantibodies to nuclear and cellular antigens, tissue inflammation and organ damage. Genome-wide association studies have shown that variants within the...
Autores principales: | Fernando, Michelle M A, Freudenberg, Jan, Lee, Annette, Morris, David Lester, Boteva, Lora, Rhodes, Benjamin, Gonzalez-Escribano, María Francisca, Lopez-Nevot, Miguel Angel, Navarra, Sandra V, Gregersen, Peter K, Martin, Javier, Vyse, Timothy J |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BMJ Group
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3329227/ https://www.ncbi.nlm.nih.gov/pubmed/22233601 http://dx.doi.org/10.1136/annrheumdis-2011-200808 |
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