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Genome-wide association study of genetic determinants of LDL-c response to atorvastatin therapy: importance of Lp(a)

We carried out a genome-wide association study (GWAS) of LDL-c response to statin using data from participants in the Collaborative Atorvastatin Diabetes Study (CARDS; n = 1,156), the Anglo-Scandinavian Cardiac Outcomes Trial (ASCOT; n = 895), and the observational phase of ASCOT (n = 651), all of w...

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Detalles Bibliográficos
Autores principales: Deshmukh, Harshal A., Colhoun, Helen M., Johnson, Toby, McKeigue, Paul M., Betteridge, D. John, Durrington, Paul N., Fuller, John H., Livingstone, Shona, Charlton-Menys, Valentine, Neil, Andrew, Poulter, Neil, Sever, Peter, Shields, Denis C., Stanton, Alice V., Chatterjee, Aurobindo, Hyde, Craig, Calle, Roberto A., DeMicco, David A., Trompet, Stella, Postmus, Iris, Ford, Ian, Jukema, J. Wouter, Caulfield, Mark, Hitman, Graham A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Biochemistry and Molecular Biology 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3329377/
https://www.ncbi.nlm.nih.gov/pubmed/22368281
http://dx.doi.org/10.1194/jlr.P021113