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The Biased Nucleotide Composition of HIV-1 Triggers Type I Interferon Response and Correlates with Subtype D Increased Pathogenicity

The genome of human immunodeficiency virus (HIV) has an average nucleotide composition strongly biased as compared to the human genome. The consequence of such nucleotide composition on HIV pathogenicity has not been investigated yet. To address this question, we analyzed the role of nucleotide bias...

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Detalles Bibliográficos
Autores principales:	Vabret, Nicolas, Bailly-Bechet, Marc, Najburg, Valérie, Müller-Trutwin, Michaela, Verrier, Bernard, Tangy, Frédéric
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3329495/ https://www.ncbi.nlm.nih.gov/pubmed/22529893 http://dx.doi.org/10.1371/journal.pone.0033502

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