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CXCL12 and [N33A]CXCL12 in 5637 and HeLa Cells: Regulating HER1 Phosphorylation via Calmodulin/Calcineurin
In the human neoplastic cell lines 5637 and HeLa, recombinant CXCL12 elicited, as expected, downstream signals via both G-protein-dependent and β-arrestin-dependent pathways responsible for inducing a rapid and a late wave, respectively, of ERK1/2 phosphorylation. In contrast, the structural variant...
Autores principales: | Rigo, Antonella, Gottardi, Michele, Damiani, Ernesto, Bonifacio, Massimiliano, Ferrarini, Isacco, Mauri, Pierluigi, Vinante, Fabrizio |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3329496/ https://www.ncbi.nlm.nih.gov/pubmed/22529914 http://dx.doi.org/10.1371/journal.pone.0034432 |
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