Cargando…

Accumulation of an Antidepressant in Vesiculogenic Membranes of Yeast Cells Triggers Autophagy

Many antidepressants are cationic amphipaths, which spontaneously accumulate in natural or reconstituted membranes in the absence of their specific protein targets. However, the clinical relevance of cellular membrane accumulation by antidepressants in the human brain is unknown and hotly debated. H...

Descripción completa

Detalles Bibliográficos
Autores principales: Chen, Jingqiu, Korostyshevsky, Daniel, Lee, Sean, Perlstein, Ethan O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3329523/
https://www.ncbi.nlm.nih.gov/pubmed/22529904
http://dx.doi.org/10.1371/journal.pone.0034024