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Signaling-Mediated Bacterial Persister Formation
Here we show that bacterial communication through indole signaling induces persistence, a phenomenon in which a subset of an isogenic bacterial population tolerates antibiotic treatment. We monitor indole-induced persister formation using microfluidics, and identify the role of oxidative stress and...
Autores principales: | Vega, Nicole M., Allison, Kyle R., Khalil, Ahmad S., Collins, James J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3329571/ https://www.ncbi.nlm.nih.gov/pubmed/22426114 http://dx.doi.org/10.1038/nchembio.915 |
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